Inhibit bacterial cell wall synthesis by binding to the penicillin-binding proteins transpeptidases on bacteria
Ofloxacin a synthetic fluoroquinolone (fluoroquinolones) antibacterial
A board-spectrum antibiotic active against both Gram-negative & Gram-positive bacteria
Acts on DNA gyrase and topoisomerase IV, enzymes which, like human topoisomerase, prevents the excessive supercoiling of DNA during replication or transcription